Last Thursday I attended the Chicago Flex User Group meeting and the topic was Adobe Flex 4 and Flash Builder 4. The Flex 4 framework brings the development of user interface to the next level. With Flex 4 the skinning and layout process is now separate from the individual objects and containers like HBox and VBox no longer exist. The container is replaced with layout definitions that is part of the skin class. It is fully integrated with Adobe Catalyst so applications can quickly be developed. I see a big potential for Domino applications running with a Adobe Flex or AIR interface.
As a result of the big announcement that Apple refuses to support Flash on the iPhone, there was definitely an anti-Apple sentiment at the meeting. A couple of Flash developers I know are switching from iPhones to Android because they are that pissed off at Apple. I personally use a Blackberry.